diff --git a/bind.go b/bind.go
index bec2e3b3a..b6cbe30c4 100644
--- a/bind.go
+++ b/bind.go
@@ -241,6 +241,10 @@ func bindData(destination any, data map[string][]string, tag string, dataFiles m
 			val.Set(reflect.MakeMap(typ))
 		}
 		for k, v := range data {
+			if len(v) == 0 {
+				// No value to bind; indexing v[0] below would panic.
+				continue
+			}
 			if isElemString {
 				val.SetMapIndex(reflect.ValueOf(k), reflect.ValueOf(v[0]))
 			} else if isElemInterface {
@@ -323,6 +327,14 @@ func bindData(destination any, data map[string][]string, tag string, dataFiles m
 			continue
 		}
 
+		// A header (or query param) whose value slice is empty is treated the
+		// same as an absent key: there is no value to bind, and the scalar
+		// paths below index inputValue[0]. Without this the bind panics with
+		// "index out of range [0] with length 0".
+		if len(inputValue) == 0 {
+			continue
+		}
+
 		// NOTE: algorithm here is not particularly sophisticated. It probably does not work with absurd types like `**[]*int`
 		// but it is smart enough to handle niche cases like `*int`,`*[]string`,`[]*int` .
 
diff --git a/bind_empty_header_test.go b/bind_empty_header_test.go
new file mode 100644
index 000000000..a252f043b
--- /dev/null
+++ b/bind_empty_header_test.go
@@ -0,0 +1,92 @@
+package echo_test
+
+// Regression tests for https://github.com/labstack/echo/issues/3169
+// "BindHeaders panics on nil or empty header value slices".
+//
+// bindData indexes inputValue[0] on the scalar-map paths and on the tagged-struct
+// paths without checking the length. A header whose value slice is nil or empty
+// therefore panicked with "index out of range [0] with length 0" instead of
+// binding nothing. An empty value slice is now treated like an absent key.
+
+import (
+	"net/http"
+	"net/http/httptest"
+	"testing"
+
+	"github.com/labstack/echo/v5"
+)
+
+func TestBindHeadersEmptyValueSlice(t *testing.T) {
+	// nil and []string{} are distinct states that both reach the same panic.
+	// They are not the same as []string{""}, which binds an empty string.
+	for name, values := range map[string][]string{
+		"nil":   nil,
+		"empty": {},
+	} {
+		t.Run(name, func(t *testing.T) {
+			e := echo.New()
+			req := httptest.NewRequest(http.MethodGet, "/", nil)
+			req.Header["X-Empty"] = values
+
+			var dst struct {
+				Value string `header:"X-Empty"`
+			}
+			if err := echo.BindHeaders(e.NewContext(req, httptest.NewRecorder()), &dst); err != nil {
+				t.Fatalf("BindHeaders returned an error: %v", err)
+			}
+			if dst.Value != "" {
+				t.Errorf("expected an empty value, got %q", dst.Value)
+			}
+		})
+	}
+}
+
+func TestBindHeadersEmptyValueSliceIntoMap(t *testing.T) {
+	// The scalar-map destination path reads v[0] as well.
+	e := echo.New()
+	req := httptest.NewRequest(http.MethodGet, "/", nil)
+	req.Header["X-Empty"] = nil
+
+	dst := map[string]string{}
+	if err := echo.BindHeaders(e.NewContext(req, httptest.NewRecorder()), &dst); err != nil {
+		t.Fatalf("BindHeaders returned an error: %v", err)
+	}
+	if _, ok := dst["X-Empty"]; ok {
+		t.Errorf("expected no entry for an empty header value, got %v", dst)
+	}
+}
+
+func TestBindHeadersPresentValueStillBinds(t *testing.T) {
+	// The guard must not swallow a header that actually has a value.
+	e := echo.New()
+	req := httptest.NewRequest(http.MethodGet, "/", nil)
+	req.Header["X-Token"] = []string{"abc123"}
+
+	var dst struct {
+		Token string `header:"X-Token"`
+	}
+	if err := echo.BindHeaders(e.NewContext(req, httptest.NewRecorder()), &dst); err != nil {
+		t.Fatalf("BindHeaders returned an error: %v", err)
+	}
+	if dst.Token != "abc123" {
+		t.Errorf("expected abc123, got %q", dst.Token)
+	}
+}
+
+func TestBindHeadersEmptyStringValueStillBinds(t *testing.T) {
+	// []string{""} is a present, empty value - distinct from an empty slice and
+	// must keep binding, so the guard keys on length and not on emptiness.
+	e := echo.New()
+	req := httptest.NewRequest(http.MethodGet, "/", nil)
+	req.Header["X-Empty"] = []string{""}
+
+	var dst struct {
+		Value string `header:"X-Empty"`
+	}
+	if err := echo.BindHeaders(e.NewContext(req, httptest.NewRecorder()), &dst); err != nil {
+		t.Fatalf("BindHeaders returned an error: %v", err)
+	}
+	if dst.Value != "" {
+		t.Errorf("expected an empty value, got %q", dst.Value)
+	}
+}